ผู้วิจัย/Authors: Chokchai Wongsinsup

ชื่อเรื่อง/Title: Dissolution Profile of Three brands Carbamazepine Tablets

แหล่งที่มา/Source: Siriraj Hospital Gazette, Vol. 45, No. 11, November 1993. Page 770-773

รายละเอียด / Details:

Three brands of carbamazepine tablets available in Thailand were assessed for their pharmaceutical properties according to the requirement of pharmacopoeial. The present study demonstrated that the dissolution profile of CBZ tablets varied markedly to the hardness of the tablet. All brands of CBZ tablet tested fulfil most of the pharmacopoeial requirements, (e.g. weight variation, content uniformity, disintegration time, etc.) except the dissolution and the friability limit. The present results indicate the problem of dissolution of CBZ tablet. However, Thai FDA has not yet required the dissolution limit for CBZ tablet. The present study therefore, provide the evidence for addition of CBZ tablet to the list of drugs that are subjected to the dissolution testing.

Keywords: carbamazepine, drug, anticonvulsant, pharmacology

ปีที่เผยแพร่/Year: 1993

Address: Department of Pharmacology, Faculty of Pharmacy, Mahidol University

Code: 00006171

ISSN/ISBN: 0125-152X

Country of publication: Thailand.

Language: English.

Category: Abstract Journal.

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