ผู้วิจัย/Authors: Chaiyaporn Yingcharoenparsuk

ชื่อเรื่อง/Title: The effect of haloperidol and chlorpromazine on salivery flow rate in male schizophrenic patients

แหล่งที่มา/Source: Journal of Mental Health of Thailand, Vol.13, No.1, January 2005, Page 39.

รายละเอียด / Details:

Schizophreine patients have high risk to oral health problem. The side effect of antipsychotics that decrease the saliva secretion is one of the contribution factors for the problem. The objective of this study is to compare the salivary flow rate in 45 male of schizophrenic inpatients treating with haloperidol and chlorpromazine with 67 male of normal volunteers. Data were gathered by keeping saliva in morning and afternoon in 3 weeks. The study was found that there was a significant lower salivery flow rate in the patient group than in control group. This was found to persist through the study period of there week but with decreasing in magnitude of difference at the end. The higher dosage of the medication taking by the patients, the lower salivery flow rate was found. In this study had indicated that Haloperidol and Chlorpromazine affects the salivary flow rate in Schizophrenic patients and this can affect patient's oral hygiene. So the surveillance for oral health problem and providing oral health care for Schizophrenic patients taking medication. Which affects the saliva flow rate, should be promoted.

Keywords: haloperidol, chlorpromazine, unstimulated whole salivary flow rate, psychotic patient, schizophrenia, psychiatry, antipsychotic, secretion, schizophrenic inpatient, halo, CPZ

ปีที่เผยแพร่/Year: 2005

Address: Prasrimahabhodi Psychiatric Hospital, Department of Mental Health

Code: 200500002

ISSN/ISBN: 2859-497-X

Country of publication: Thailand

Language: English.

Category: Abstract Journal.

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