ผู้วิจัย/Authors: Chaiyaporn Yingcharoenparsuk

ชื่อเรื่อง/Title: The effect of haloperidol and chlorpromazine on salivary flow rate in male schizophrenic

แหล่งที่มา/Source: Journal of Mental Health of Thailand, Vol.13, No. 1, January 2005, Page 38-45.

รายละเอียด / Details:

Schizophrenic patients have high risk to oral health problem. The side effect of antipsychotics that decrease the saliva secretion is one of the contribution factors for the problem. The objective of this study is to compare the salivary flow rate in 45 male of scizophrenic inpatients treating with halopromazine with 67 male of normal volunteers. Data were gathered by keeping saliva in morning and afternoon in 3 weeks. The study was found that there was a significant lower salivary flow rate in the patient than in control group. This was found to persist through the study period of three week but with decreasing in magnitude of difference at the end. The higher dosage of the medication taking by the patients, the lower salivary flow rate was found. In this study had indicated that Haloperidol and Chlorpromazine affects the salivary flow rate in Schizoprenic patients and this can affect patient's oral hygienc. So the surveillance for oral health problem and providing oral health care for Schizophrenic patients taking medication, which affects the saliva flow rate, should be promoted .

Keywords: haloperidol, chlorpromazine, halo, chlorpro, antipsychotic drug, schizophrenia, saliva, oral hygine, unstimulated whole salivary flow rate, psychiatry

ปีที่เผยแพร่/Year: 2005

Address: Prasrimahabhodi Psychiatric Hospital, Department of Mental Health

Code: 2005000039

ISSN/ISBN: 2859-497-X

Country of publication: Thailand

Language: English.

Category: Abstract Journal.

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