ผู้วิจัย/Authors: Suwanna Arunpongpaisal.

ชื่อเรื่อง/Title: Development of Khon Kaen University Depression Inventory (KKU-DI) as a Depressive Measurement for North-eastern Thai Population.

แหล่งที่มา/Source: Journal of the Psychiatric Association of Thailand. Vol.51, No.3, July-September 2006, Page 330-348.

รายละเอียด / Details:

Objective to develop a valid and reliable screening instrument Khon Kaen University Depression Inventory (KKU-DI) for depressive disorders in North-eastern Thailand. Method Items in KKU-DI were developed using a mixture of focus group and experts panel discussions. The first draft of KKU-DI consisted of 80 items and scaling response was rating from 1 to 4 based on direct estimation technique. Content validity testing was done using experts opinions from other 10 psychiatrists and 3 psychologists. Thereby items had been reduced into 35 items. Then reliability study was done to examine internal consistency Cronbach alpha coefficient by using 270 subjects 135 psychiatric cases and 135 normal subjects. Finally items were tailed into 30 items each scored on 0-3 scale final score ranging between 0-90 KKU-DI items was tested in field study using two stage screening procedure in 6 rural and 2 urban villages of Amphur Muang Khon Kaen. First stage home visit interview and the KKU-DI tests were administered by 7 research assistants with well trained in using KKU-DI. Then they randomly selected 10% of the subjects who had score of KKU-DI as 0.20% of the subjects who had score of KKU-DI as 1-20 and subjects who had score of KKU-DI more than 20 all these samples were sent to the second stage. This stage psychiatric interview by anyone of three psychiatrists for probate depressed cases were carried out independently. Inter-rather reliability among the three psychiatrists was also examined and adjusted until accepted. We compared the KKU-DI score to a clinical diagnosis made by an experienced psychiatrist using. Composite International Diagnostic Interview (CIDI) as the gold standard for diagnosis of depressive disorders to examine sensitivity specificity and optimum cut-off point of this instrument. Results The 951 subjects were recruited to this study Demographic characters of subjects varied. Participants in the two focus groups were 11 males and 13 females median 28 years while subjects in the reliability study were 95 males and 175 females with median 35 years and subjects in the field study were 292 males and 385 females median 39 years. Female was predominated and the majority of samples were in the middle to late adulthood married (83-84%) low education attainment and were engaged in agricultural work Internal consistency of the instrument was high Cronbach alpha coefficient 0.945 Inter-rater reliability among 7 research assistants was good. Fleiss generalized kappa 0.80 95% CI=0.75-086p‹0.001. The 3 psychiatrists had a high inter-rater reliability in diagnosis. Fleiss generalized kappa 0.85 (95%CI=0.74-0.98 p<0.001). The sensitivity of the KKU-DI was 88% (95% CI=86-90%) and specificity was 88% (95%CI=86-90%) under optimum cut-off point scores of 20 Prevalence of depressives disorders in the community was 3.9% with female predominance and ratio 8.4 :1. Conclusion The KKU-DI is a valid and reliable screening instrument for depressive disorders in North-eastern Thailand Sensitivity 88% (95%CI=86-90%) specificity 88% (95%CI=86-90%) under optimum cut off point scores of 20.

Keywords: depressive disorder, depress, screening test, khon kaen university depression inventory, KKU-DI, screening instrument, validity, reliability, sensitivity, specificity, psychiatrist, psychiatry, diagnosis

ปีที่เผยแพร่/Year: 2006

Address: Department of Psychiatry, Faculty of Medicine, Khon Kaen University.

Code: 200700036

ISSN/ISBN: 0125-6985

Country of publication: Thailand.

Language: English

Category: Abstract Journal.

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