ผู้วิจัย/Authors: Paritat Silpakit, M.D. Kittipong Sanichwanakul, M.D. Phunnapa Kittirattanapaiboon, M.D. Kittiwan Tiam-Kaew, M.D. Surachet Pongtanya, M.D.

ชื่อเรื่อง/Title: Intramuscular Clonazepam for the Treatment of Violent Psychotic Patients

แหล่งที่มา/Source: Journal of The Psychiatric Association of Thailand, Vol. 44 No.2 April-June 1999, P 134-139.

รายละเอียด / Details:

Objective The purpose of this study was to examine the efficacy of intramuscular clonazepam in the treatment of violent hospitalized psychotic patients. Method Forty-nine violent hospitalized psychotic patients were randomly assigned to two groups receiving clonazepam 1 or 2 mg intramuscularly. The assessment of the severity of violence was done by trained nurses using Staff Observation Aggression Scale (SOAS) at baseline, 30, and 60 minutes after treatment. The data was analyzed by student t-test. Results Mean aggression score was reduced significantly in both groups of patients (clonazepam 1 or 2 mg I.M.) at 30 and 60 minutes after treatment (p‹0.05). Comparing between two groups of patients, the aggression score was not different significantly at 30 and 60 minutes after treatment (p>0.05). Conclusion Intramuscular clonazepam was effective and safe in treatment of violent psychotic patients. One milligram of clonazepam can decrease violent behavior within 30 minutes.

Keywords: psychotic patients, violence, clonazepam, Staff Observation Aggression Scale, SOAS, psychiatry, violent, psychosis, drug, pharmacology, treatment

ปีที่เผยแพร่/Year: 1999

Address: Suanprung Psychiatric Hospital, ChangLor Road, Chiangmai 50100

Code: 00000125

ISSN/ISBN: 0125-6985

Country of publication: Thailand.

Language: English.

Category: Abstract Journal.

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