ฐานข้อมูลวิจัยด้านสุขภาพจิตและจิตเวช

ผู้วิจัย/Authors: Pramote Sripochai

ชื่อเรื่อง/Title: A randomized controlled trial of weight control program for clozapine induced weight gain.

แหล่งที่มา/Source: Journal of Mental Health of Thailand, Vol.16, No. 2, May 2551, Page 99.

รายละเอียด / Details:

Objective: To determine the effects of weight control program in weight gain schizophrenic patients receiving clozapine. Meterials and methods: The randomized controlled trial was conducted in 58 schizophrenic patients receiving clozapine and body mass index (BMI) equal or more than 23 kg/m2. Patients were allocated to either a control group (n=30) receiving routine services or to an intervention group (n=28) having a weight control program. The program comprised a motivation interview wit the patients to induce behavior change. Education on nutrition and exercise was given. Discussed and set plan with the patients for every month and lasted for 6 months. Changes from baseline in the following parameters were compared between the groups body weight body mass index (BMI) and waist circumferences by t-test. Results: The maximum weight lost which found in the intervention group was 12 kgs. BMI was significant reduced from baseline. Four patients in intervention group could reduce BMI from baseline to less 23 kg/m2 (number needed to treat=7). The waist circumferences reduction was not significant different from the control group. Amount of patients in the intervention group was satisfied with benefit and necessities of program were 21 and 27. Conclusion: The weight control program for management weight gain from clozapine could reduce body weight effectively. The satisfactions were at medium to high level.

Keywords: clozapine, schizophrenia, weight control program, BMI, body weight

ปีที่เผยแพร่/Year: 2008

Address: Suansaranrom Hospital

Code: 20080058

ISSN/ISBN: 2859-497-X

Country of publication: Thailand

Language: English

Category: Abstract

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