ฐานข้อมูลวิจัยด้านสุขภาพจิตและจิตเวช

ผู้วิจัย/Authors: Anggoon Patarakorn

ชื่อเรื่อง/Title: Comparison of Zuclopenthixol accuphase, haloperidol and diazepam in alcohol withdrawal symptoms.

แหล่งที่มา/Source: Journal of Mental Health of Thailand, Vol.15, No. 3, September 2550, Page 163.

รายละเอียด / Details:

Objective: To compare the efficacy off zuclopenthixol accuphase, haloperidol and diazepam for alcohol withdrawal symptoms (AWS). Materials and methods: This respective study was performed in 90 selected in-patient cases admitted to Thanyarak Institute from 1 February till 30 April 2007. there were 3 groups of treatments i.e. group-1 was received diazepam intravenous alone; group-2 received zuclopenthixol accuphase intramuscular add-on diazepam intravenous and group-3 received haloperidol intramuscular add-on diazepam intra-venous. CIWA-air was applied to assess AWS, the amount of diazepam, number of the day receiving each drug and adverse effects of the treatment were monitored. Means percentage were analyzed. Monitoring scale was compared by ANOVA and Chi square tests. Results: Almost male patients at average age of 46 years old. The severity of AWS was at moderate level. Zuclopentthixol acuphase add-on diazepam treatment could calm patients more effective than diazepam alone and the amount of diazepam was less significantly. However when compared with the group of haloperidol add-on diazepam, the results were comparable but it had less adverse effects. Conclusion: Zuclopenthixol accuphase intramuscular add-on diazepam intra -venous provided better result in treatment of AWS than diazepam alone and its adverse effects were less than that of haloperidol though the efficacy was comparable. However further were designed study should be carried out.

Keywords: alcohol withdrawal, diazepam, haloperidol, zuclopenthixol accuphase, efficacy, alcohol withdrawal symptoms (AWS)

ปีที่เผยแพร่/Year: 2008

Address: Thanyarak Institute, Department of Mental Services

Code: 200800343

ISSN/ISBN: 2859-497-X

Country of publication: Thailand

Language: English

Category: Abstract

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