ผู้วิจัย/Authors: Worrawat Chanpattana, M.D.

ชื่อเรื่อง/Title: Seizure Threshold in ECT: Differences between Instruments.

แหล่งที่มา/Source: Journal of The Psychiatric Association of Thailand, Vol. 45 No.2 April-June 2000 P 145-153.

รายละเอียด / Details:

Objective Determination of seizure threshold can help guide selection of stimulus dosage in electroconvulsive therapy (ECT); nonetheless, this threshold is subject to a variety of influences. This study aimed to measured the effect of the selection of ECT instrument on initial seizure threshold. Method The initial seizure threshold was measured by stimulus dose titration in 88 patients, according to titration schedules with uniform increments. Treatment was given with the MECTA SR1 or the Thymatron DGx instrument, by random assignment, in groups with three age-related stratifications. Results Measured seizure thresholds were higher with the stimuli used from the MECTA instrument than from the Thymatron instrument in 79% of patients (overall p ‹ 0.0001), and were on average 61% higher (overall p < 0.0001). Conclusions Because greater side effects appear to accompany stimuli with higher seizure thresholds, these differences may have clinical implications. Moreover, when different ECT instruments are used on the same patient, adjustment of the stimulus dosage should be considered.

Keywords: electroconvulsive therapy (ECT), seizure threshold, effects of ECT, psychiatry, psychosis

ปีที่เผยแพร่/Year: 2000

Address: Department of Psychiatry, Srinakharinwirot University, 681 Samsen, Dusit, Bangkok 10300.

Code: 00000310

ISSN/ISBN: 0125-6985

Country of publication: Thailand.

Language: English.

Category: Abstract Journal.

Download: -