ฐานข้อมูลวิจัยด้านสุขภาพจิตและจิตเวช

ผู้วิจัย/Authors: Umporn Benjaponpitak

ชื่อเรื่อง/Title: Acamprosate as an alternative in the treatment of alcohol addiction

แหล่งที่มา/Source: Journal of The Psychiatric Association of Thailand, Vol. 42 No.2 April-June 1997, P 107-112.

รายละเอียด / Details:

Problems of alcohol dependence produce dramatic costs to society in terms of lost productivity, social disorder and avoidable health care utilization. Based on reasonable expectations of addiction treatments, clinical trials have shown effectiveness of treatment strategies. Besides psychosocial aspects, various studies have focused on neurotransmitter and recepter systems that may be implicated in alcohol tolerance and dependence. Acamprosate, a GABAergic agonist is one of the relatively new drugs that yield promising result. This article discusses the possible mechanisms of action of acamprosate as well as reviews animal and human studies that support the use of acamprosate in the treatment of alcohol dependence.

Keywords: alcohol dependence, alcohol addic, drug abuse, treatment

ปีที่เผยแพร่/Year: 1997

Address: Department of Mental Health Ministry of Public Health.

Code: 0000066

ISSN/ISBN: 0125-6985

Country of publication: Thailand.

Language: English.

Category: Abstract Journal.

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