ฐานข้อมูลวิจัยด้านสุขภาพจิตและจิตเวช

ผู้วิจัย/Authors: Surachet Pongtanya

ชื่อเรื่อง/Title: Effectiveness of haloperidol in treating patient with amphetamine-induced psychosis

แหล่งที่มา/Source: Journal of The Psychiatric Association of Thailand, Vol. 47 No.2 April-June 2002. P. 119

รายละเอียด / Details:

Objective To determine the efficacy of high-dose haloperidol (10-15 mg/day) and low-dose haloperidol (4-8 mg/day) in treating patients with acute amphetamine-induced psychosis Method An open-label four-week clinical study was conducted with 40 patients aged 15 to 40-years-old with acute amphetamine-induced psychosis wno sought treatment at Suanprung Hospital. The patients were equally randomly assigned to treatment with either high-dose haloperidol (10-15 mg/day) or low-dose haloperidol (4-8 mg/day) for a period of four weeks.The efficacy of the treatment was assessed using the Positive and Negatives Syndrome Scale (PANSS) Results High-dose of haloperidol (10-15 mg/day) and low-dose of haloperidol (4-8 mg/day) yielded similar resulis when used to treat patients with acute amphetamine-induced psychosis. There was a significant reduction in the PANSS total scores-positive, negative, general psychopathology and cluster scores-in both groups when compared to the basekine (p‹0.001). Conclusion Haloperidol in both high and low doses is an effective treatment of acute amphetamine-induced psycchosis

Keywords: amphetamine, psychosis, effectiveness, haloperidol, halo antipsychotic drugs, major tranquilizer

ปีที่เผยแพร่/Year: 2002

Address: The Psychiatric Association of Thailand.

Code: 0000127

ISSN/ISBN: 0125-6985

Country of publication: Thailand.

Language: English.

Category: Abstract Journal.

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